Like Fable 2 and Mass Effect, Gothic 3 will place heavy emphasis on moral decision making as a means to influence every aspect of your game experience. Faction allegiance is also important, and there will be plenty of guilds to join and masters to learn from. Now, all publisher Aspyr needs to do is clean up the English voiceovers from their German counterparts. Viel Glück!
See also: Single player RPGs are alive and well