http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/ Engadget Comments for Mini DNA replicator costs $10 http://www.engadget.com/media/feedlogo.gif http://www.engadget.com en-us Copyright 2012 Weblogs, Inc. The contents of this feed are available for non-commercial use only. Blogsmith http://www.blogsmith.com/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 10:02AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/Im going to allow it.]]>May 7th 2007 1:49PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
I can replicate the same device with a match, spooon, mineral oil, ice cube and thermometer. There, i've designed a $1 PCR machine, but its not going to be very good.]]>May 4th 2007 10:25AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/If one of the tubes can be held at 4°C then you could have a "hold" cycle like you would on any PCR machine. Oh, and the earliest PCR "machines" really were just a tech with three water baths and a timer. My boss used to do it that way in college. Worked just fine.
This may not seem very exciting to most people, but when you do this stuff for a living it's very cool to see how cheap the technology has become.
Oh, and does polymerase chain reaction really need quotes? It's not some magic pseudoscience word, it's the standard process by which DNA is replicated.
]]>May 4th 2007 10:35AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
Thanks for the reply bud! I'm not sure that device could lower temp to 4°C. You could always toss the entire device into an icebath... we could add salt to make sure that the water could conduct electricity as well :-)

Plus, its all about yeild. a good tech with a $4k Machine will do a better job than a good tech with a $10 machine. ]]>May 4th 2007 11:15AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 12:27PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
You still need a thermometer, which at minimum is a buck. The more controlled the environment, the higher the yeild, so a machine is always better than cups.]]>May 4th 2007 1:46PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.newscientist.com/article.ns?id=dn11763&feedId=online-news_rss20

I hate playing follow the links...]]>May 4th 2007 10:29AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 11:15AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 11:30AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
I did PCR using water baths for a quite a while until thermocyclers were released commercially. Worked just fine.]]>May 4th 2007 12:02PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
Also, yes, it's 10$ a machine. But you need to add the actual reagents (enzymes, nucleotides, primers) which aren't cheap.

Still, I'm going to talk to my PI about getting us a few of this for the lab... ;)]]>May 4th 2007 11:22AMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 12:53PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/@Tito... "Still, I'm going to talk to my PI "
You've got a private investigator? Waycool!]]>May 4th 2007 12:54PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/

100 ul ~ $50]]>May 4th 2007 1:08PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 3:16PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 4th 2007 3:11PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/-your PI]]>May 4th 2007 3:33PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
"The harder you work, the faster I get tenure!"]]>May 4th 2007 5:19PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 5th 2007 12:20PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/May 5th 2007 8:11PMhttp://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/http://www.engadget.com/2007/05/04/mini-dna-replicator-costs-10/
Seriously, dumping the DNA of a small-time looser or the guy who stole your high-school sweetheart at the crime scene is hella lot easier than faking fingerprints.]]>May 17th 2007 8:55PM