Say what you will about Nintendo, they know how to create new market segments. Case in point, the SmartBrains "State of the Brain Fitness Software Market 2008 report" which cites the Nintendo's Brain Age games as a key driver in growing the brain fitness software market to a $225 million industry, up 125% since 2005.
Though Brain Age games dominate the $80 million consumer segment of the market, the game has also been a key inspiration to the 20 companies that create similar brain training tools for everything from sports teams to the military. The various brain training products have been used in over 400 elder care facilities and five successful randomized clinical trials. One product even gained FDA approval for use in stroke rehabilitation. We just hope those stroke patients don't have an accent.