Atanasov and Dilov cover a lot of ground in the interview, talking about the lack of pre-defined player roles in comparison to traditional MMOs, as well as the fact that gameplay will evolve primarily due to the choices available to players (and their inevitable consequences). The skill system is also discussed, and, though no concrete details are given, Dilov does mention the fact that players aren't restricted in terms of what skills they can learn, nor is there any need for a respec mechanic. Dilov also makes clear that the crafting system is intended to be similarly complex and dynamic, with the learning curve evolving over time based on the ever-changing economy.
"Earthrise will bring a breath of fresh air to the MMO genre, which is choking with class-based or free-to-play titles that introduce a lot of limitations to the player. We are going in a direction that I believe many people are looking for," Atanasov says.
[Thanks to Super Healer for the tip.]