The Draenor Perks are intriguing, and as someone who plays a rogue, they made me take a long look at what they meant for the class as a whole. Between Draenor Perks, spell changes, and the spells being removed, it appears combat rogues are moving further into dealing immediate, direct damage, with a lower focus on DoT abilities. Combat rogues no longer have Rupture and Draenor Perks turn a combat rogue's Deadly Poison into Instant Poison. There's an active effort to differentiate class specs that have lost their unique flavor over the years. I'm interested to see how changes like this play out.
This is, of course, only the beginning of an alpha -- everything we've seen so far still has plenty of time to change.