The Wii U's cost and you
I personally would have to re-think my possible purchase it the Wii U turns out to be more than $299, especially seeing as many launch titles will just be games that will already be available on the Xbox 360 & PS3, but with "Wii U" specific controls.
The Wii became a very popular console because of the price (among other factors)
I don't see Nintendo changing their strategy, and a $299 launch seems appropriate with the new technology they are bringing in
The 3DS was launched at a $249 price point, even though Nintendo attempted to justify the boost in technology with the 3D without glasses tech.
Seeing as Nintendo will not only be producing a "next-gen" console as well as a controller that has a touch-screen on it and interacts with the Wii U in a number of ways, I HOPE it sells for $299, but I wouldn't be surprised if it sold for more than that.