Roxio released an update to their flagship CD and DVD-burning software for Macintosh this morning. Version 7.1 is now a universal binary and provides fixes with issues related to Quicktime 7.1, AppleScript, the Toast Setup Assistant, and encoding Apple Lossless files.
There aren't too many more applications on my Intel iMac that are not universal binary. The Adobe CS2 suite and Microsoft Office, of course, are the two outstanding holdouts. Virtually everything else has been updated to work natively on an Intel iMac. What other applications are you waiting for?