We haven't even gotten the first Professor Layton adventure yet, and we're already seeing screens of the sequel. Professor Layton and the Devil's Box looks much like the first game, which is to say, gorgeously lush.
The game's scope is expanded from that of its predecessor: the professor and his student Luke have access to a train, which acts not only as a vehicle for traveling to multiple towns (or multiple Curious Villages, if you prefer), but is also the venue for its own puzzles.
These screenshots are best coupled with IGN's preview of the game, for the complete screenshot/description package. The Famitsu page has the same information, but in a less convenient language.