MobileMe, goodbye .Mac (and good riddance). Apple's synchronization and web application solution for your Macs, PCs, iPod touch or iPhone is now live. Push eMail, push contacts, and push calendar and a new suite of web applications are now yours for the taking. You know, after you hand over $99 for the first year or $149 for a one-year family subscription.
P.S. Things are loading slowly at the moment as the service comes up.
Update: As noted in the comments, the site is now down for most people.
Update 2: It's coming up again but it's still flaky as hell. We've managed to get to our calendar, contacts, and settings but Mail is still a no, no.
Update 3: And... it's down again. Nice going.