Destroy All Humans! Big Willy Unleashed. Though
With the game being designed specifically for the Wii, "the controls simply didn't translate well, and instead of pushing out the product with translated controls, it was cancelled." From the player's perspective, it sounds like it was the humane thing to do, but we wonder how many PSP games would be left if all developers adopted this particular stance on controls.
[Via PSP Fanboy]