Sonic Chronicles may lead to more familiar franchises for BioWare's handheld division, according to statements made by Chronicles lead Miles Holmes. Holmes says that the company is considering DS versions of its major franchises, including Dragon Age, Jade Empire, and Mass Effect. "Basically anything that reinforces the franchises," said Holmes.
His choice? "I tell you which one I would want. I want the Mass Effect one." He goes on to say that "a DS version would be an awesome way to keep interest alive and keep it going in addition to the next [Mass Effect game]."
Is this a confirmation of a Mass Effect DS sequel? Absolutely not, but it shows that BioWare is at least thinking about their own games on DS.