If you haven't heard yet, that 1% chance to miss with spells that has always been in place that you couldn't overcome with Hit on your gear, no matter how much you had? Kalgan confirms that it is gone. Gone like the wind! As of Wrath, at least. Are you excited? I'm excited.
In all seriousness, I find this to be a fantastic change. That 1% chance to miss no matter what you did was always annoying to me, and it was one of those random factors that could ruin your day no matter how good of a player you are and how good your gear is, both in PvE and PvP. That resisted Fear or Frost Nova in a pinch shouldn't happen anymore, if you gear properly.
Rogues? This helps you guys, too. Since your hit rating applies to both melee and spells, your poisons will benefit from +Hit, and you can reach that point where your poisons are never resisted. Exciting? Exciting!