New York City's flagship Apple Store, located on 5th Avenue in Manhattan, is doing tremendous business. According to The New York Post, that store raked in $440 million in one year. Of course, the location doesn't hurt. It's right by Central Park and the huge, glass cube is a real tourist draw.
The Post also notes that the SoHo store pulled in $100 million, but didn't provide any stats on the West 14th Street store. In the meantime, construction has begun on what's rumored to be a fourth NYC store, expected to open at the corner of 67th and Broadway on Manhattan's Upper West Side later this year. If that store and a rumored Brooklyn store are opened, NYC would boast six stores total (including the Staten Island store).
Apple intends to open 25 new stores for fiscal year 2009, half of them outside the United States.