Resident Evil story entirely in clay, you'll get no argument from us. RE is a series known for horror, and it's surprisingly difficult to build tension when you know severed limbs could be re-attached with nary a fingertip's worth of pressure.
But we'd argue that the bolder choice is casting the most relaxed dude ever as Chris Redfield. Somehow, when he can't even be bothered to modulate his pitch for a giant man-eating python, he becomes even more badass. It's like Matthew McConaughey joined STARS. See for yourself right after the break.