We just came across a great podcast the other day that's focused on all things sci-fi: Galactic Watercooler. Although it's not a gaming podcast, their latest episode (#176) is all about EVE Online. The GWC hosts are apparently really into playing EVE and they talk about the game's setting of New Eden in the context of David Weber's Honorverse series of military sci-fi novels, drawing parallels between the two in terms of strategy and technology. They also discuss the things they've seen and done in their time in the game, from their first steps into (and fleeing from) PvP to a run-in with a virtual prostitute. (You're free to do many things in EVE's sandbox... but that is probably not one of them.)
The hosts are given a hand in relating what they've gotten from the game experience in EVE Online by two notable players. Ian Chisholm, the creator of the award-winning Clear Skies machinima and its excellent follow-up, explains how he tells his own stories in the game visually. He also discusses what drives him to invest so much of his time and effort into the projects, and the technical challenges in making Clear Skies a reality. A fantastic interview.