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Researchers develop programmable molecular circuitry for living cells

Laura June

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Researchers at the UCSF School of Pharmacy's Department of Pharmaceutical Chemistry, led by Christopher A. Voigt have just published a paper which promises to get your circuits moving. The team has been working with E. coli bacteria to build logic gates like the ones found in computers directly into cells, making it possible to rewire and program them. The simple logic gates used in the experiment were built into genes then inserted into E. coli cells. The logic gates then acted as the communicator between the separate strains, allowing them to be connected together.The use of logic gates in cells could make it possible to tackle more complicated processes, so that science can begin to use cells at the molecular level for biomedical advances.

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