Domino will make an appearance in Deadpool, according to the Merc with a Mouth himself. Just as he did in San Diego earlier this year, Deadpool showed up during a Marvel games panel at the New York Comic-Con last week and, after confronting his dancing alter-ego, said that the Rob Liefeld-created Domino, a.k.a. Neena Thurman, would be showing up in the upcoming game from High Moon Studios.
Unfortunately, that's all he decided to share during his very raucous appearance. High Moon is reportedly hard at work on the game, and Deadpool promised it's still set for a release sometime next year.