The Binding of Isaac may be a bit premature, since right at the end he discusses a new way that the game will live on, in a console version published by Nicalis. It's called The Binding of Isaac: Rebirth, and it will feature local co-op, revamped 16-bit graphics, and a second expansion, alongside Wrath of the Lamb, that didn't make it to the Flash version.
McMillen says he was hesitant to develop another console title, after Super Meat Boy on XBLA ate up two years of his life. One of his guidelines in working with Nicalis is that he won't "deal with anything when it came to business."
The Binding of Isaac has sold more than 1 million copies on PC and Mac in its first year on Steam, and 25 percent of those people bought the Wrath of the Lamb expansion as well. That's up from 700,000 full copies reported in June.
There's no consensus on which consoles will get Rebirth, but in February McMillen noted he was looking at "1-2 Sony platforms." In the postmortem, he names Microsoft and Sony's digital platforms, as well as a Nintendo eShop release for Wii U or 3DS, the last of which is a one-eighty from that relationship earlier this year.