Apple, in its ongoing battle over an e-book price fixing scandal, has been dealt yet another setback. Last month, Judge Denise Cote ruled that Apple had violated antitrust laws in conspiring with publishers to raise e-book prices. Cupertino asked for a temporary suspension of her ruling while it sought to appeal the penalties leveled against it, but today Judge Cote refused that request. The company maintains its innocence, and its co-defendants have jumped to its defense in the wake of a strong restrictions handed down by the Justice Department. But, increasingly, it appears that Apple is fighting a losing battle. We're sure that there are still tricks in its legal arsenal, but there is little indication that Cupertino will be able to avoid terminating its existing agreements with publishers and will be barred from engaging in agency pricing before the end of the DoJ's five-year ban.