The Harmony One, Logitech's flagship universal remote, uses the Harmony database of over 200k products to manage up to fifteen devices for your setup -- even including media PCs and air conditioners. The less expensive Harmony 700 is limited by controlling up to six devices (and has fewer multi-device macros for common actions), and doesn't have the One's charging cradle and lighter battery. Really, about the only trick the touchscreen-enabled One is missing is the ability to control devices in your basement or closet (if you need something to do that, check out the more expensive Harmony 900). Just beware the Harmony desktop app; although the device database is frequently updated, the configuration software is extraordinarily painful to use. Fortunately, you won't need it very often.