WashingtonUniversitySchoolOfMedicine

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    Gene editing could lead to a vaccine for arthritis

    by 
    Jon Fingas
    Jon Fingas
    04.30.2017

    Right now, arthritis treatment tends to be an all-or-nothing proposition: the drugs you take affect your entire body, causing havoc with your immune system and leaving you prone to infections. But how do you narrow the treatment to just those areas where you feel pain? Genetics, apparently. Researchers have used CRISPR gene editing to turn stem cells into cartilage that releases a biological anti-inflammatory drug when they encounter inflammation. It not only limits treatment to the affected area, but responds only when there's a pain flare. You only get relief when you need it.

  • Brain monitoring chips dissolve when you're done with them

    by 
    Jon Fingas
    Jon Fingas
    01.18.2016

    By far the biggest danger of brain implants is rejection -- it can be just a matter of time before your immune system freaks out and makes a bad situation that much worse. That's where Washington University might come to the rescue. Its researchers have crafted tiny (smaller than a pencil tip) wireless brain sensors that dissolve. Their mix of silicone and polylactic-co-glycolic acid (PLGA) is sophisticated enough to transmit vital data like cranial pressure and temperature, but melts after a few days of exposure to typical organic matter.