Biotechnology
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FDA clears emergency use of lab-made antibodies to treat COVID-19
The FDA has cleared the use of Regeneron's lab-made antibodies to treat COVID-19, but only in some cases.
Lab-grown stem cells may carry an increased risk of cancer
If you've followed the latest medical research, you know that stem cells are a big deal. They let you repurpose cells so that you can theoretically grow them into whatever you need. However, scientists just got a good reason to be more cautious than they have in the past. A Harvard team has discovered that five of the 140 human embryonic stem cell lines registered for research use in US labs have cells whose mutations can cause cancer. Two of the lines have been used in human trials, too. None of those patients has developed cancer, thankfully, but there's a "very real risk" it could happen.
Paralyzed man regains use of arms thanks to 'wireless spinal cord'
Remember that paralyzed guy from Southern California who managed to walk on his own accord thanks to a revolutionary technique that bridged the gap in his severed spinal column with a wireless Bluetooth link? A team of doctors at Ohio's Case Western Reserve University have reportedly accomplished the same feat with a patient's arms.
Genome testing is now easy, fast and pretty
Genome testing gear doesn't get a lot of love. Like a lot of lab equipment, it tends to be ugly and unwieldy -- it's not designed with the same elegance as the smartphone in your pocket. Mercifully, the crew at Fluidigm appears to have solved those problems in one shot with its Juno genotyping machine. The Yves Behar-designed device is (dare we say it) pretty, and wouldn't look out of place sitting on a desk. It's also more intuitive, relying on a large, simple touchscreen interface instead of keyboards and tiny displays.
Apple and Microsoft help form lobby group opposing attempts to kill software patents (update: not lobbying)
Few would object to legislative attempts to stop patent trolls in their tracks. However, several companies are worried these efforts might go too far -- enough so that they've formed their own US political lobby organization, the Partnership for American Innovation. The group, which includes tech giants Apple, GE, IBM and Microsoft, wants a "balanced" approach that reduces the volume of junk patents (and the resulting abuse) while letting companies file for software and biotech patents. The policy isn't surprising when these firms are trying to protect their cash cows. However, it also pits the Partnership's members squarely against firms like Netflix and Twitter, which argue that patents only get in the way. No matter what lawmakers do, it's now clear that they're going to get an earful from both sides. Update: Despite what it looks like at first glance, the Partnership is strictly a public advocacy group, not a lobby.
Researchers pit microorganisms in deadly game of 'PAC-mecium'
At first glance, the so-called "biotic games" research conducted by a Stanford University team that's installed microorganisms into crude, real-life video games merely raises the question: Wow -- that's a job? A summary of the team's experimentation on living organisms (red flag!) in this month's Lab on a Chip journal suggests that biotic games could "have significant conceptual and cost-reducing effects on biotechnology and eventually health care," not to mention that they could also "educate society at large to support personal medical decisions and the public discourse on bio-related issues." Those sure sound like complicatedly-worded, yet noble goals -- or at least good cover for playing video games all day -- but we sense a distressing undertone in the work here. Just watch the clip (after the break) of the researchers' Pac-Man prototype clone, "PAC-mecium," wherein, ostensibly, a player would "guide" unwitting paramecia to happy-face yeast pellets and attempt to keep the poor protozoa from being devoured by a giant zebrafish larvae, or not. It's pretty clear to us that the next "guinea pigs" in this diabolical plan will be mice, and then probably monkeys. The final stage? Gerard Butler.
Megaframe Imager takes its one million frames-per-second capabilities to the medical world
The iconic Megaframe Imager has been kicking for a good while now, but gurus have been scratching their heads in an effort to figure out how to best take advantage of a sensor that can capture one million frames per second. A European consortium made up of the NPL, ST Microelectronics, the University of Edinburgh, and TU Delft have something in mind, and not surprisingly, it's in the medical realm. Researchers are currently looking to use this here device in "cellular / sub-cellular imaging; neural imaging; biochemical sensors; DNA / protein microarray scanning; automotive collision studies; and high-sensitivity astronomical observations," and for the first time, tests are proving that it could be a vital tool in the future of biosensing. Tangled in technobabble? Here's the long and short of it: a crew has demonstrated "detection of viral DNA binding events using fluorescence lifetime imaging at the very low target concentrations relevant in biosensing applications with acquisition times of less than 30 seconds," something that should be useful in disease screening, mutation and forensic analysis. So much for escaping the jargon, huh?
Microscopic microscope could fit on cellphones, cost just $10
Make no mistake, microscopes have been getting increasingly smaller for years, but a team of CalTech researchers have leapfrogged previous efforts by creating one minuscule enough to fit on a cellphone. The microscopic optofluidic microscope could one day be used in third-world nations to "analyze blood samples for malaria or check water supplies for giardia and other pathogens," and given that it could theoretically be mass produced for around $10, cost shouldn't be too much of a hindrance. Changhuei Yang, credited for developing the chip, is currently chatting it up with biotech companies in order to get this to the market, but there's no word yet on any takers.[Via Physorg]
New tech keeps tabs on your liver via cellphone
In the scheme of things, blood alcohol-screening phones probably stand to save more lives than... uh, Glutamine Oxaloacetic Transaminase and Glutamine Pyruvic Transaminase (affectionately known as GOT and GPT) screening phones, but health tech is health tech, and we've no doubt there's someone out there who's going to benefit from this. A crack team at Korea's Research Institute of Bioscience and Biotechnology has developed a sensor that monitors GOT and GPT -- key indicators of liver function -- and uploads key stats via phone, presumably to a hospital or other interested parties. So if you've had the exact same idea kicking around for a while, sorry to say you might as well drop it now; the patent apps are filed and the team plans to pursue commercialization in the near future.[Via textually.org]
