Guitar synthesizer
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Jamstik Studio is the MIDI guitar you might actually want to use
Guitar MIDI controllers are usually giant disappointments. But Jamstik seems to have broken the code. The Studio MIDI Guitar has fast and accurate pitch detection, and even does an impressive job of recreating bends, hammer-ons and to a lesser degree slides. MIDI wasn’t designed with stringed instruments in mind, so it’s never going to be perfect, and the $800 asking price is steep. But, this is probably the best guitar-style MIDI controller on the market right now. Plus, it’s actually a guitar.
Boss' SY-1000 is a synth orchestra you control with a guitar
There's more than one way to turn a guitar into a synthesizer. But Boss and Roland have always gone for the most elaborate and complicated approach. While the new SY-1000 can be played simply by plugging in a guitar or bass via a standard 1/4-inch instrument jack, it really shines when connected via Roland's proprietary GK pickup. Unlike a lot of other guitar synth pedals, the GK pickup system allows for polyphonic tracking of notes on a guitar without the use of MIDI, which can be a little unreliable. The SY-1000 builds on the tech in the SY-300 which turns your guitar licks into everything from a gnarly synth lead to a rich pad, or even a thick Leslie-like organ.