It's designed for professional test labs or even businesses where host-rigs must be protected against faulty USB devices. But there's nothing stopping you from decorating a living-room wall
with this second-generation 49-port USB 2.0 hub from Cambrionix. Unless you consider the cost -- £399 / $657 (plus tax) -- or the fact that it requires an ATX-2 power supply to push 500mA across all 49-ports significant deterrents.
Cambrionix 49-port USB hub for professional nerds