Copy off Springboard, patch it, put it back onto your device and reboot. It's what I'm running on my iPhone and touch right now and it works beautifully.
Of course, once you have all that space available to work with, what are you going to do with it? I put together a TUAW webpage launcher using the OpenURL kit I posted about a few weeks ago. Now I just tap to launch TUAW.
If you'd like to download your own TUAW launcher, you can grab a copy from the Samples folder in my OpenURL kit. You'll also find instructions there for creating your own website launchers.
Over at website "Jon's Thoughts on Everything", you can find a web-based equivalent of OpenURL. I actually found it harder to use. For me, it involved more work than just adding an icon and editing two lines of text but you might enjoy using it.