NC State gurus find 'Goldilocks' of DNA self-assembly, look to improve drug-delivery vehicles

Darren Murph
D. Murph|10.28.10

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NC State gurus find 'Goldilocks' of DNA self-assembly, look to improve drug-delivery vehicles
We're guessing that most Wolfpackers in the greater Raleigh area are in full-on tailgate mode right now, but aside from laying a beating on the Seminoles this evening, NC State faithful are also trumpeting a new DNA discovery that could one day make it easy to get vital drugs to hard-to-reach places within you. Researchers from the university have purportedly discovered the 'Goldilocks' of DNA self-assembly, which holds promise for technologies ranging from drug delivery to molecular sensors. The concept, known as DNA-assisted self-assembly, has been vastly improved by using "computer simulations of DNA strands to identify the optimal length of a DNA strand for self-assembly." You see, perfection occurs when strands aren't long enough to intertwine with each other, yet not short enough to simply fold over on each other. We know, it's a lot to wrap your brain around with half a hot dog shoved in your mouth, but hit the video after the break for a... shall we say, more visual explanation.

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