Unfortunately, Wheeler has proven to be one of the stronger proponents of net neutrality we've seen in the government in recent years, so losing his voice will undoubtably be a setback. The FCC's Open Internet Order, passed in February of 2015, was a key piece of legislation helping to keep the internet free from evils such as paid prioritization and throttling of certain services, two things the massive telecoms are looking to as ways to milk more money out of customers and content companies alike.
But now, with Trump's administration ready to take over, these rules are under significant threat. As a president with a clear pro-business agenda, Trump doesn't seem to mind trampling on the notion of a free internet if it'll make massive companies a few more dollars. With Wheeler stepping aside, we'll now have to wait to see who Trump appoints to the open position.