Secunia ranks Apple first in software insecurity, Safari said to have AutoFill vulnerability
One vulnerability that is potentially serious, however, is an issue with Safari's AutoFill feature recently discovered by Jeremiah Grossman of WhiteHat Security. According to Grossman, a malicious website can exploit the feature to pull data from a user's address book without their knowledge, which has been demonstrated to take "mere seconds" by a bit of proof of concept code (you can try out yourself if you're feeling trusting). Grossman also says he's informed Apple of the vulnerability but hasn't received a response, and suggests that the only "fix" in the meantime is to turn off the AutoFill feature completely.
Update: AllThingsD has a statement from Apple on the AutoFill issue — a spokesperson says "we take security and privacy very seriously," and that, "we're aware of the issue and working on a fix."