If you can surmount the language barrier, feel free to gleefully bring Nintendo's next turnbased roommate adventure Pokemon dating card RPG to America, even if they won't.
[Update 1: Gamesindustry.biz reports that Nintendo UK says the Wii is region-locked. This is contrary to Perrin Kaplan's statements, though her exact comments may have been misinterpreted to begin with. It's possible that Kaplan implied first-party games would specifically be region-free -- which is not the same thing as saying the console is region-free. After all, one can play region-free DVDs on a region-locked DVD player. Not that the Wii can play DVDs anymore...]
[Update 2: It was too good to be true.]