Several folks in our most recent Ask TUAW post were complaining about Spotlight's interface, so it's rather serendipitous that today I ran across Spotlaser. This app provides a much more useful search interface to Spotlight by making it easier both to run searches by allowing boolean operators (e.g. AND, OR, NOT), wildcards, and more. And even better, the results are displayed as a Smart Folder in a Finder window (above) rather than Spotlight's default, hard-to-use list. For those of you fed up with trying to use Spotlight, give Spotlaser a whirl and see if it makes your searching go better.
Spotlaser is a free download, but the developer requests donations.