Gray Matter, for a few years. Gray Matter is the story of a neurobiologist and his assistant, who must investigate both his reappearing dead wife and his history of creepy experiments. And also solve puzzles, obviously.
In a retrospective Gabriel Knight interview with Edge, Jensen said that Wii fans may have reason to watch the constant delays of the point-and-click adventure game: "There are plans for a Wii port of Gray Matter, and I hope it happens." The website currently says it's "coming soon 2009", so, barring further delays, we can expect to hear more about this purported Wii version ... sometime this year.