There's Grand Theft Ovid, which tells some of the Roman poet's tales using everyone's favorite carjack simulator (along with a few other popular games). Modal Kombat features a set of guitar controllers that are used to play non-music games. The best, though, might be the Theater of the Arcade, which takes old games like Duck Hunt and Donkey Kong and presents them, re-imagined, as short theatrical vignettes. O Mario, Mario, wherefore art thou?
The shows are going on at the Brick through the rest of July. Performances are just $15, plus there's also a Rock Band Karaoke night and a few other game-related events sprinkled throughout the run. If your significant other is complaining that you're spending too many nights in front of the TV and not enough out enjoying the arts, this seems like a perfect compromise.