The on-screen pages look very nice. They are easy to read, and the content gets more space than it does in Pulse. You have some limited, but helpful, control over the font style and size. Every story has a sidebar that allows you to rate it so that Zite understands your interests. When you launch Zite, a page of top stories appears. Over the last few days, I've noticed Zite adjusting the content to things I've been most focused on.
There are some negatives. I don't have enough control over eliminating stuff I don't like. In the pets topic, I chose birds as subject matter, but I got dozens of stories about Angry Birds. I told Zite that I didn't like those in the Pets section, but it still insists on putting them there. They are slowly going away, though. Another issue is that once you select sections based on your interests, you can't change the order of those sections. I also think Zite doesn't respond quickly enough to my likes and dislikes. Over time I can see the mix of content change, but I'd like it to be faster.
I find I am using Zite multiple times a day. While RSS feed based apps like Pulse are fine, they don't include the discovery of information that Zite pulls off so well. Some people will complain that you can't add RSS feeds on your own to Zite, and that is true. There are, of course, lots of apps that do that, and Zite is something different; it focuses on content itself more than specific sources. On the other hand, you can tell Zite you like a particular source, and it will continue to appear. Think of Zite like Pandora. It knows what you are reading and creates a magazine that exists only for you.
The GUI is lovely, and the app will surely improve. If you're hooked on news and information, I suggest you download Zite and see what you think.