Speaker and amplifier choice is a personal thing, with some focusing on sound quality and others preferring form over function. If you are looking for something unique, then you should check out this Analog Tele-Phonographer spotted by Boing Boing and crafted by Christopher Locke.
Each unit is handmade from salvaged trumpets and other brass instruments. It's technically an amplifier so it doesn't need any external power source to fill a small room with music. Because of how they are made, each one is unique both in appearance and performance.
[Via Boing Boing]