Previous-gen consoles (are they officially previous-gen now?) like the Xbox 360, PS3 and Wii could be controlled by certain Harmony models in the past. The Xbox 360 was controlled via an IR sensor, while the PS3 and Wii were controlled via Bluetooth. The Logitech website doesn't specify how the Xbox One and Harmony remotes communicate, but each new Microsoft console does come with a big rectangle that blasts IR signals. We'll let you do the math and speculation from there.
The Xbox One currently lacks a first-party remote such as the Xbox 360 Media Remote, but in the meantime, the Harmony remotes will get you around your dashboard if, say, you don't want to talk to your console, wave your hands or use the controller.