injections
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Hydrogel injections could increase wounded soldier survival rates
If a team of researchers from MIT and Texas A&M University have their way, wounded soldiers will have soon have a better chance of survival. The project is a biodegradable gelatin that once injected, helps with blood coagulation, cutting down on blood loss internally. In some trials, the hydrogel decreased the time it took for the blood to clot by 77 percent after it maneuvered into position. The medical solution is still in the testing phase, but once its perfected, researchers hope to see soldiers add preloaded syringes packed with the material to their gear arsenals. [Image credit: Behrouz Mehri/AFP/Getty Images]
Scared of needles? Try swallowing them
If you're one of the many who fear needles, you might be in luck. Researchers at MIT and Massachusetts General Hospital are working on an oral alternative to injections, and it involves the use of a capsule. On the pill's surface, tiny needles inject drugs directly into the lining of the stomach once it's swallowed. During trials, insulin was delivered more efficiently, and the capsule didn't cause any issues as it passed through the digestive system. While insulin was used in tests, the delivery system is said to be most helpful for antibodies to treat cancer and autoimmune disorders. At any rate, those of us who prefer to avoid shots entirely may soon have one less source of anxiety during doctor's visits. [Image credit: Christine Daniloff/MIT]
Ceramic microneedles to make injections painless
Rest assured, we've "seen" methods of delivering injections sans pain, but we've yet to actually experience this phenomenon ourselves. If Dr. Roger Narayan has anything to do about it, however, we may not feel even a pinch the next time the blood drive comes calling. A team of researchers led by the aforementioned individual has reportedly been able to use "two-photon polymerization of organically modified ceramic (Ormocer) hybrid materials to create microneedles resistant to breakage," and they can also be made in a wider range of sizes than metal counterparts. It's said that these very needles would be "so fine that patients wouldn't feel them piercing their skin," and while that sure sounds delightful, we've no idea how many more visits we'll make before finding one of these in the nurse's hand.[Via medGadget, image courtesy of Rice]
NanoPass needles set to vaccinate sans pain
Given the choice, even we'd take the pills over the vaccination, but a new Israeli startup is hoping to ease the fears so commonly associated with needles. NanoPass Technologies is working to develop its "proprietary intradermal drug delivery technology," which supposedly deliver injections without the painful side effects by actually not reaching the nerve endings of the skin. Based on MicroPyramids, which are manufactured by MEMS (Micro Electro Mechanical Systems), the pure silicone crystals are used in extremely diminutive microneedles for intradermal injections, and the tip of the device measures less than one-micrometer in diameter. The company touts its pain-free technology (sound familiar?) as a breakthrough that is "non-intimitdating," which should reduce the likelihood of fainting both youngsters (okay, and adults) face when dealing with needles, and is even said to be easier to administer. Unfortunately, we've got no good news proclaiming that these will be replacing intramuscular and subcutaneous methods later this week, but the $6.5 million in funding that the company has acquired should go pretty far is helping its cause. [Via MedGadget]
