lungs
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Researchers create lung 'blueprint' that could aid organ regeneration
Serious lung disease has a high rate of mortality, and the only curative treatment is a lung transplant. This is a complicated procedure that has other adverse health effects and oftentimes simply doesn't work, so for scientists in this field, organ regeneration -- that is, growing an organ from the body's own tissue -- is the ultimate solution. Now, researchers from Yale say they're on track for this very eventuality.
Google sees a future in wearable-free health monitoring
Google and its Alphabet parent haven't been shy about their interest in digital health, and now they're taking that curiosity in an unusual but potentially very helpful direction. GeekWire reports that Google has acquired Senosis Health, a Seattle-area startup whose focus was on turning smartphones into health monitoring tools. Its apps used a phone's built-in sensors to perform checkups that would normally require a dedicated sensor: HemaApp checks your blood's hemoglobin count using your phone's camera, for example, while SpiroSmart uses the microphone to measure your lung functions.
Most e-cigarettes have chemicals that will hurt your lungs
Electronic cigarettes are ostensibly safer for you than conventional cigs (you're not inhaling tar and other elements of tobacco smoke), but it now looks like they might not be much better at all. Researchers have found that 75 percent of flavored e-cigs contain diacetyl, a flavoring chemical that can produce "popcorn lung" disease when inhaled over the long term. To boot, many of the tested flavors had other related chemicals (like 2,3-pentanedione and acetoin) on top of known risky ingredients, such as formaldehyde.
Researchers battle a deadly lung problem with meds, computer models
It doesn't take a whole lot to stop the tiny air sacs in your lungs from doing their jobs -- trauma, a nasty case of pneumonia or sepsis could lead to what's called Acute Respiratory Distress Syndrome, a situation in which your blood doesn't get all the oxygen it should. ARDS can be tricky to treat even on a good day, but that's where the big brains at the University of Michigan come in. Researchers there have cooked up a way to model how liquid medication surges and diffuses throughout the lungs, and breathed new life into a treatment that others had all but given up on in the process.
Some e-cigarette flavors may have toxic effects on lung cells
E-cigarettes may be a popular alternative to the traditional smoke sticks, despite contrasting opinions on how safe they are. Adding to the list of harmful effects, the American Thoracic Society published research at its annual conference that certain flavors used in vaping liquid may alter cells in lung tissue. During the study, researchers exposed human airway epithelial cells to doses of 13 e-cig flavors for periods of 30 minutes and 24 hours. 5 of the 13 displayed "adverse effects to cells in a dose-dependent manner." Of those five, three flavors -- Hot Cinnamon Candies, Banana Pudding (Southern Style), and Menthol Tobacco -- were toxic to lung cells at higher doses in the 30-minute test. What's more, when cells were exposed for 24 hours, the same trio of flavors stunted cell growth as the dosage increased. Also of note: the flavorings' negative effects didn't occur with nicotine or the e-liquid vehicle on its own (propylene glycol and vegetable glycerin).
Japanese scientists create giant metal cilium, relief for Voltron's giant metal lungs (video)
Why would a group of researchers develop a table full of rods that mimic the movements of microscopic hairs? It's a fair question, and Keio University's Yusuke Kamiyama certainly doesn't offer up much in the way of real world applications for such technology. He is, however, happy to demonstrate the cool functionality of the metallic cilium, which appear to drift around as though underwater, until coming into contact with an external stimuli. The rods react to touch by congregating near the area of contact, with movements executed by biometal rods that communicate with an external PC. Scientists hope that research from the project will be useful at some point, but in the meantime, at least we know where to turn if we get a major mucus blockage. Video after the break.
Rat lungs successfully grown in bioreactor: groundbreaking, yet also kind of gross
Bioartifical organs differ from, well, plain ol' artificial organs because they consist of biomaterials and cells. And while bioartificial livers are becoming increasingly commonplace, it's only recently that working lungs have been grown in a lab. Working at the Massachusetts General Hospital and Harvard Medical School in Boston, researchers removed the left lungs from rats and stripped them of cells with a process that left the blood vessels, airways, and connective tissues intact. Using all that as a sort of scaffolding, lung cells were regrown on the scaffolding in a bioreactor. The cultivation of the lungs took less than a week, and once they'd been run through their paces in culture, they were transplanted into rats. At this point, the lungs did their job for about six hours, after which "they failed through accumulation of fluid inside the lung and resultant capillary leakage," according to PhysOrg. According to the man in charge, Mass General's Harald C. Ott, if work continues at the current pace we might begin to see regenerated organs for human patients within the next ten years. To see the thing in action, hit up that source link.
Researchers create functioning human lung on a microchip
Researchers at Harvard University have successfully created a functioning, respirating human 'lung' on a chip in a lab. Made using human and blood vessel cells and a microchip, the translucent lung is far simpler in terms of observation than traditional, actual human lungs (for obvious reasons), in a small convenient package about the size of a pencil eraser. The researchers have demonstrated its effectiveness and are now moving toward showing its ability to replicate gas exchange between lung cells and the bloodstream. Down the road a bit more, the team hopes to produce other organs on chips, and hook them all up to the already operational heart on a chip. And somewhere in the world, Margaret Atwood and her pigoons are rejoicing, right? Here's to the future. Video description of the device is below.
Snoozy the Sloth is a breathing, napping toy after our own hearts
You know what would have been awesome to have as a toy when we were growing up? Not a baby to swaddle and feed, or a Barbie doll to dress up and imagine careers for, or a fake pet to worry about neglecting. No, we'd have preferred Snoozy the Sloth, who merely breathes and take naps with you when you cuddle him. The sloth's epic simplicity -- a plush toy with Arduino guts and a 2 DC motor diaphragm to pump the air in his "lungs" -- makes him a perfect companion for our downtime. Created by Justin Blinder for a toy-making class at Parsons The New School for Design, Snoozy is merely a prototype, but we really hope the toy industry is watching: they could learn a lot, in our sleepy, sleepy opinion. There's a video of him napping after the break (and hit the read link for a shorter one of his innards). Yawn.[Via Gizmodo, thanks, Jesse]
Haemair envisions external prosthetic lung and respiratory aid
We're not exactly sure how we feel about an external lung (okay, we're completely grossed out, but we're a bunch of pansies when it comes to this stuff anyway), but a Welsh company is looking to introduce one such device in order to aid those with breathing problems. Haemair's Respiratory Aid and Prosthetic Lung would theoretically be worn around the belt and incorporated with a "complete prosthetic lung that will employ no electrical or mechanical parts." By being external, it enables it to be easily maintained, and the simple reversibility is important for "treating emergency and acute cases for which the device might be needed for no more than hours or weeks." As of now, the company is still developing the final product, but just as soon as it can establish that maintenance-free operation is feasible over the long-term, consider the game decidedly "on."[Via medGadget]
Smoking Jacket catches smoke, darkens symbolic lungs
We've seen jackets that alert you when approaching uncomfortable scenarios, light up on demand, and track the poor soul trapped within, but Fiona Carswell's iteration does a number on smokers who don't mind warning labels. Similar in craftiness to the Ruyan e-cigarette, the Smoking Jacket sports a stylish white exterior with a pair of symbolic lungs and a sophisticated internal tubing system. The aptly-dubbed "visceral, absurd information displays" morph from pristine air containers to dark, murky caverns as smokers blow excess smoke into a tube located in the collar. The one-way air valve traps smoke in the lungs, creating a relatively repulsive sight in the eyes of both onlookers and smokers alike. Of course, Fiona can't promise that such a dramatic effort will faze the hardcore puffers, but trying to continually ignore the disgusted faces looking your way as you walk by would be challenging indeed.[Via WMMNA]
