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Lasers and smart pills could eventually replace injections
While getting shots or blood work isn't anyone's idea of fun, roughly 10 to 20 percent of American adults suffer from trypanophobia, the extreme fear of hypodermic needles and injections. This phobia can prevent people from partaking in routine medical exams, receiving life-saving vaccines or even properly managing their blood-glucose levels (should they suffer from diabetes). However, a pair of novel injection systems offers the promise of putting those critical medicines into our bodies without ever breaking the skin.
Startup lab Theranos scales back unique 'finger prick' blood tests
Theranos, the $9 billion Silicon Valley startup that promises blood test results with just a finger prick, is under serious scrutiny. According to The Wall Street Journal, FDA investigators recently showed up unannounced to inspect its laboratory, due to concerns about the data the company voluntarily submitted for approval of its testing methods. So far, the FDA has only approved one (for herpes) of the 100 Theranos tests waiting for its endorsement. Since the agency also marked the "nanotainers" -- containers that can keep tiny amounts of blood -- Theranos uses as "unapproved medical devices," the company was forced to stop drawing blood by pricking patients' fingers unless it's to check for herpes. In short, it has almost completely stopped doing what makes the startup unique, making it like any other lab, with needles, syringes and such. Update (10/16): Founder Elizabeth Holmes had an interview with Jim Cramer on CNBC today (you can view it after the break), and Theranos has published another blog post promising "Unprecedented transparency." It confirms that the finger prick tests are only being performed to check for herpes, saying that it sought out and asked the FDA to review and fully clear its technology for other tests.
Scared of needles? Try swallowing them
If you're one of the many who fear needles, you might be in luck. Researchers at MIT and Massachusetts General Hospital are working on an oral alternative to injections, and it involves the use of a capsule. On the pill's surface, tiny needles inject drugs directly into the lining of the stomach once it's swallowed. During trials, insulin was delivered more efficiently, and the capsule didn't cause any issues as it passed through the digestive system. While insulin was used in tests, the delivery system is said to be most helpful for antibodies to treat cancer and autoimmune disorders. At any rate, those of us who prefer to avoid shots entirely may soon have one less source of anxiety during doctor's visits. [Image credit: Christine Daniloff/MIT]
This purple, talking box can save you from an accidental prescription overdose
How's this for a crazy statistic: according to the Center for Disease Control and Prevention, more people die each year from drug overdoses than car accidents -- and 70 percent of those deaths are caused by legally prescribed medication. Kaleo, a pharmaceutical firm, hopes it can change that. It's creating a device called Evzio, a small, easy to use drug delivery system that can safely administer a life-saving dose of naloxone. This device could save the lives of thousands of patients who have been prescribed legal opiates to treat pain. Not sure how to use it? Don't worry about it: it talks.
Vaccine-delivery patch uses microneedles to do its dirty work, looks good in testing
This dissolving microneedle patch has been in development for well over a year now, but Mark Prausnitz -- a professor in the Georgia Tech School of Chemical and Biomolecular Engineering -- along with a number of other GT and Emory University colleagues, have just now wrapped up a lab trial that brings it that much closer to market. As the story goes, this vaccine-delivery patch, which is based on hundreds of microscopic needles that dissolve into the skin, was recently seen as reliable in a round of mice tests, and the powers that be have also concluded that these patches would cost "cost about the same as conventional needle-and-syringe techniques, and may lower the overall cost of immunization programs by reducing personnel costs and waste disposal requirements." Oh, and did we mention that you could apply 'em on your own with little to no pain? FDA approval, we're waitin' on ya.
Knitted mitts for the Alliance
We are so glad we get to use bigger pictures now, especially when they show off something this cool. Mirthical made these Alliance-branded fingerless mitts (actually, we're not sure that lion is an official Alliance logo, but he's cute enough) for a friend of hers who was such a big Warcraft fan that she put an Alliance crest on her wedding cake, too.The design is great, though -- she borrowed the cuff look from a neckwarmer, and that lion came from a sticker someone else made. We're not sure why you'd wear open gloves like that (probably a girly thing), but even if they aren't super warm, they do at least look comfy. And Alliance have to represent when they can, we guess. Grab your... mittens and fight the Horde?
Venus wearable monitor could offer alternative to needles
It looks like folks wary of needles now have yet another piece of technology to look forward to, with this so-called Venus device promising to measure tissue oxygen and pH levels without the need to draw any blood at all. To do that, the system makes use of a relatively small sensor that's placed directly on the skin, which uses near infrared light to measure to measure the blood and analyze both the tissue oxygen and pH, as well as the the metabolic rate. As a bonus, the lack of needles also reduces the the risk of infection, and it's relatively portable nature makes it ideal for use outside of strictly medical situations, such as monitoring athletes -- or astronauts, as it was originally developed for. As you might expect, however, the device is still just in prototype form, and there doesn't appear to be any indication as to when it might move beyond the lab.
iPhone speaker too quiet? Stab it with needles
If you're like us, you feel more than a little annoyed with iPhone's speaker volume. Yes, whether you're waiting for a call, trying to have a speakerphone conversation, or just listening for sweet DTMF tones -- the thing kind of stinks. Perhaps it's time to take extreme measures, as some owners have resorted to... like sticking a needle through the holes in the speaker enclosure. Yes, according to daring "modders," it's possible to get a 40-percent increase in volume via this simple-yet-destructive trick of perforating the thin plastic which covers the speaker. Apparently, the phone gets so loud post-surgery that the volume is actually startling to some users. Feeling like you're brave enough to really void that warranty? Let us know the results![Thanks, Michael]
NanoPass needles set to vaccinate sans pain
Given the choice, even we'd take the pills over the vaccination, but a new Israeli startup is hoping to ease the fears so commonly associated with needles. NanoPass Technologies is working to develop its "proprietary intradermal drug delivery technology," which supposedly deliver injections without the painful side effects by actually not reaching the nerve endings of the skin. Based on MicroPyramids, which are manufactured by MEMS (Micro Electro Mechanical Systems), the pure silicone crystals are used in extremely diminutive microneedles for intradermal injections, and the tip of the device measures less than one-micrometer in diameter. The company touts its pain-free technology (sound familiar?) as a breakthrough that is "non-intimitdating," which should reduce the likelihood of fainting both youngsters (okay, and adults) face when dealing with needles, and is even said to be easier to administer. Unfortunately, we've got no good news proclaiming that these will be replacing intramuscular and subcutaneous methods later this week, but the $6.5 million in funding that the company has acquired should go pretty far is helping its cause. [Via MedGadget]
