The defining use for the Wii Opera browser, is, of course, watching all the insanity of YouTube on your fancy-big TV. The site, however, is not quite conducive to the low-resolution viewing conditions found on the Wii, and is thus rather inconvenient to browse effectively.
Enter: SofaTube. A website dedicated to the perusing of not only YouTube but also the Revver library of videos, using a convenient drag-and-drop interface and large text for easy reading. So sit back, relax, and enjoy that Opie and Anthony video one more time ... it's that easy.
(That link involves some NSFW and rather gross comedy, though we can't seem to take our eyes off it. Click at your own risk.)