There's no need to skim through Microsoft's CES press release any longer, we have the only piece of information you need to know right here:
"And for casual gamers, the company demonstrated a cross-platform game of "UNO!," with some players joining from their Windows Vista-based PCs and others joining from their Xbox 360 consoles."
That's right, folks, UNO! (note the exclamation point for added awesomeness) is Live Anywhere. Why bother with a gun-toting space marine when you can inflict massive damage with the ego-shattering Wild Draw 4 ... anywhere. Sure, IPTV is cool if you're into that thing. We'll take UNO Anywhere.