As we've previously mentioned, the Metroid-inspired Commodore 64 game Turrican might be making a return to systems, courtesy of original developer Factor 5. In yet another interview, this time with Gamasutra, president Julian Eggebrecht mentioned that they are still exploring ways to bring this series back.
He's particularly intrigued with the way that Metroid Prime helped relaunch that franchise, turning it from a sidescroller into 3D, and wants to do the same with Turrican. Maybe without looking so much like Metroid this time around.
The trouble is, any time you roll your character up into a ball, people are going to scream Metroid ... so get to work on fixing that, Factor 5.