There are a bewildering array of options in MMOs. Which race? Which class? Factions, specs, spells ... and, of course, crafting professions. EverQuest 2's fantastic crafting developer Domino attempts to answer the question of "what profession should I pick" with a wealth of experience and firsthand knowledge. The essence of her advice can be boiled down to "do what seems like fun". Crafting is already a specialized experience; you don't want to be stuck making something boring. She offers up a number of assets on top of that, suggesting that every tradeskiller complete the artisan level tutorial quests. Domino links into the EQ2 Traders Corner guides, the Tradeskill discussion boards, and even a guide for what kind of house to buy (got to put all that stuff somewhere).
In a related thread, Domino touches on the future of EQ2 crafting. A plea from a weaponsmith has touched off an epic discussion of crafting itemization, and the tradeskill maven has commented on her future plans throughout. If you're a crafter of any kind in EQ2, make sure and page through some of these comments; they're a glimpse of what we might see in GU 45 and beyond.