Sloane and MacHale's Mysterious Story is, like Level-5's Professor Layton series, a collection of brain teasers wrapped up in an overarching mystery tale. The puzzle content in this game consists of lateral thinking puzzles from Paul Sloane and Des MacHale, presented as both animated scenarios (in a very cool silhouette style) and text. The puzzles seem to involve moving the text of the puzzle around with the stylus to make connections.
Of course, Level-5 has yet to say anything about localization on Mysterious Story. We'd say it's an obvious choice given the success of Professor Layton, but we have yet to see any of the Layton sequels!