"I was really hooked on Wizardry the PC game, and that's kind of where I got the inspiration for the Slime," Dragon Quest producer Yuji Horii told MTV Multiplayer. "There's ... slime-looking characters [in Wizardry], so I got the inspiration from it. I was doodling the slime-looking character and I took it to Mr. Toriyama, who did the character design, and he made it the Slime we see today."
The Slime went on to appear not only in every Dragon Quest game, but also in its own games, along with plenty of adorable merchandise.