But you can totally do that, as Ubisoft has added 3D support to Assassin's Creed: Revelations. You can enjoy the illusion of depth whether you have a 3D television or not: the PS3 and Xbox 360 versions use TriOviz's tech for normal TVs, and are also compatible with all 3DTVs. The PC version uses Nvidia's 3D Vision technology.
Speaking of hookblades and sickness, have fun zipping over cities with 3D turned on. And by "have fun" we mean "keep a bucket handy."