Laika Believes, by Austin-based Minicore Studios, presupposes a world in which not only did Laika (the first animal to orbit the earth!) survive her historic voyage, but she returned as a super cyborg dog for some reason. And ... she returned to a world dominated by a Soviet superpower.
This depressing (except for the superdog) alternate reality forms the basis of a Metroidvania-type platformer for PC and XBLA about resisting the world takeover, starring a character with "a novel defensive mechanic that lets players turn the firepower of Laika's enemies against them." All the company has shown so far is concept art, but it's art for a concept strong enough to keep our attention.