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Harvard scientists reverse aging in mice, laugh maniacally at human possibilities
The reversal of aging has been one of the great dreams of humanity, but it seems like our rodent overlords have beat us to it. The Harvard Medical School has demonstrated "a dramatic reversal" in the aging process when reintroducing the enzyme telomerase into old and feeble mice. What happened was that their naturally worn out organs started to regenerate, instead of degenerating further, bringing them back to a youthful state of health. Sadly, while the results of this study are hugely important, there are a couple of caveats to make: firstly, the mice in question were genetically modified to suffer from a lack of telomerase, which might have inflated the results of the tests relative to regular mice, but more importantly, an increase in telomerase in humans is "a hallmark of most human cancers." So, if you want a shot of Benjamin Button brew, you'll have to be very patient indeed. For now, let's just be happy that Algernon and his buddies have found their fountain of youth. [Thanks, Vygantas]
Lichborne: State of the Death Knight
Welcome to Lichborne, WoW Insider's newest class column. Every week in Lichborne, Daniel Whitcomb will explore the ins and outs of Blizzard's newest class, the Death Knight. It's Wrath of the Lich King Beta time, and finally time to meet the new Death Knight class. Unfortunately, we can't really guarantee you'll be meeting the same class that you'll see in the live game, per se. It's not that the class isn't shaping up well or isn't quite distinctive, it's more that there's just so much that's changing. The next build that's scheduled to hit the Beta servers is a perfect example. Not only will talent trees be changing extensively, with some talents becoming baseline and some baseline abilities becoming talents, some talents switching tiers, and others even switching trees, but the very way we inflict and stack diseases will be getting some tweaking as well. In addition, many of the Death Knight's baseline abilities, especially related to disease and damage rotations, are changing as well. So with all these changes, what can you say about a class that's changing drastically on a weekly basis, and may look completely different from how it does now by the time Wrath goes live? Is it really possible to speak about an overarching unifying theory of Death Knights? Well, let's try. Welcome to the first annual State of the Death Knight address.
Point your single oversized eyeball at this Resident Evil: Degeneration trailer
Comic Con 08 attendees were recently treated to a new, two-minute trailer for the upcoming CGI motion picture Resident Evil: Degeneration. The series' previous, lackluster live action installments enveloped our hard hearts in a thick shell of apprehension towards the new movie when it was first announced -- but after seeing it in action, consider said shell shucked. Not only does it look gorgeous, but it appears Leon and Claire will be voiced by Paul Mercier and Alyson Court, the two characters' voice actors from Resident Evil 4 and Resident Evil: Veronica, respectively. It's also full of valuable Pro-Tips for those playing along at home! Shoot them in the head, eh? Thanks, Leon!
The Art of War(craft): Dreaming about Death Knight PvP
I know, I know. It's too early to actually figure out how Death Knights will work in PvP. Humor me for a bit. The new class, with its juicy talents and abilities, even if they will get changed before Wrath of the Lich King hits the shelves, have got me really excited. They have some pretty cool spells and a new resource mechanic that promises to shake things up as far as gameplay is concerned. I'm not big on alts, and I play mostly on my main and a secondary toon that really needs more love, but I actually want to make a Death Knight. I'm not an alt-o-holic, but I think I'll be taking it all the way to Level 80.Of course, while I tell all my friends that I'm finally making a toon I'll be happy to tank with, what I'm really thinking about is PvP. I had initially wanted to make a Death Knight class when the game was announced, Death Knights being my favorite Hero in Warcraft 3. I thought Warlocks were the going to be it, considering the Death Coil spell, but I ended up never making a Warlock at all. But now here's the real deal. Plate armor, badass Rune weapons, Deathchargers, and all things ooky, spooky, and vile. Sounds like a lot of fun to me.
WWI '08 Death Knight Demo: Unholy spells and talents
Unholy was originally touted as the PvP DPS tree. What it appears to do rather well, though, are diseases and minions. If your vision of a Death Knight is close to a Diablo 2 Necromancer type, leading an army of undead minions and spreading plague and exploding corpses across the land, Unholy is probably going to be the tree for you. Of course, your crowd control is probably going to be a little peeved at you with all those DoTs, but that's what AE spells like Death and Decay and Unholy Blight are for, right? Unholy also seems to include quite a bit of utility, including the ability to resist lots of spells and status effects, and some debilitating debuffs, so it could be called a utility tree of sorts as well. Here's a list of some of the Unholy spells and talents available in the WWI Demo: Unholy Spells: Death GateRequires level 55Costs 1 Unholy Rune10 second cast, 15 minute cooldownDescription: Returns you to Ebon Hold (Note: Since Ebon Hold is not yet implemented, in the demo it returned you to Tirion Fordring). Death GripRequires level 55Costs 1 Unholy RuneInstant cast, 35 second cooldown.30 yard rangeDescription: Harness the unholy energy that surrounds and binds all matter, drawing the target toward the Death Knight and forcing the enemy to attack the Death Knight for 3 seconds.Plague Strike Requires level 55Costs 1 Blood Rune and 1 Unholy RuneInstant cast Melee rangeDescription: A vicious strike that deals weapon damage plus 37 and plagues the target, dealing 350 shadow damage over 12 seconds. Raise Dead Requires level 56 Costs 2 Unholy RunesInstant cast30 yard rangeDescription: Raises a ghoul from a corpse to fight by your side. if the target corpse is not humanoid, Corpse Dust must be supplied to complete the spell.Death Strike Requires level 58Costs 1 Unholy RuneDescription: A deadly attack that deals 60% weapon damage. if the target dies within 6 sec and yields exp or honor, Death Strike heals the Death Knight for 406 damage.Death and DecayRequires level 60Costs 1 Unholy Rune, 1 Blood Rune, 1 Frost Rune.30 second cooldown30 yard rangeDescription: 100 shadow damage modified by Attack Power is inflicted every 2 seconds to all targets in the affected area for 10 seconds. Has a chance to cause affected targets to cower in fearDegenerationRequires level 62 Costs 1 Unholy RuneDescription: Instantly attack the target, dealing 60% weapon damage and inflicting a disease dealing 91 damage over 21 seconds. Any existing heal over time spells on the target become corrupted, dramatically increasing the damage done by the disease and removing the healing effect. Stacks up to 3 times.Unholy PresenceRequires level 70 Description: Imbues the Death Knight with unholy fury, increasing attack speed by 15% and reducing the global cooldown on all Death Knight abilities by 0.5 seconds.Anti-Magic Shell Requires level 75Costs 1 Unholy Rune20 second cooldownDescription: Surrounds the Death Knight in an anti-magic shell, absorbing 75% of the damage dealt by the next harmful spell. Damage absorbed by anti-magic shell energizes the Death Knight with additional runic power. Lasts 5 seconds.Army of the DeadRequires level 80 Costs 2 Unholy Runes10 minute cooldownDescription: Summons an entire legion of your best ghouls to fight by your side.
