DnaStrand

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  • Harvard stores 704TB in a gram of DNA, may have us shopping for organically-grown storage (video)

    by 
    Jon Fingas
    Jon Fingas
    08.19.2012

    Early research has had DNA making circuits and little factories. We haven't really seen DNA used as a storage medium, however, and it's evident we've been missing out. A Harvard team led by George Church, Sriram Kosuri and Yuan Gao can stuff 96 bits into a DNA strand by treating each base (A, C, G, T) as though it's a binary value. The genetic sequence is then synthesized by a microfluidic chip that matches up that sequence with its position in a relevant data set, even when all the DNA strands are out of order. The technique doesn't sound like much on its own, but the microscopic size amounts to a gigantic amount of information at a scale we can see: about 704TB of data fits into a cubic millimeter, or more than you'd get out of a few hundred hard drives. Caveats? The processing time is currently too slow for time-sensitive content, and cells with living DNA would destroy the strands too quickly to make them viable for anything more than just transfers. All the same, such density and a lifespan of eons could have us turning to DNA storage not just for personal backups, but for backing up humanity's collective knowledge. We're less ambitious -- we'd most like to know if we'll be buying organic hard drives alongside the fair trade coffee and locally-sourced fruit.

  • Nanopore DNA sequencing technique promises entire genome in minutes or your money back

    by 
    Tim Stevens
    Tim Stevens
    12.24.2010

    Those vaguely affordable DNA tests that promise to tell you just how likely you are to be stricken by some horrible and unavoidable genetic affliction in the future? They only look at a tiny fraction of the bits and bobs and bases that make up your genetic code. There's a race on to develop a quick and inexpensive way to sequence a human's entire genome, a process that costs about a million thousands of dollars now and takes ages but, via the technique under development at Imperial College London, could be done in a few minutes for a couple of bucks in 10 years. The process relies on nanopores, which are the go-to tech for companies trying to pull this off. Basically, a DNA strand is pushed through a 2nm hole on a silicon chip and, as it moves through, that chip is able to use an electrical charge to read the strand's coding sequence. That is then spit out to a supercomputer to crunch the numbers at a speed of 10 million bases per second and, within minutes, you too can have some hard data to make you freak out about the future -- and maybe a place to put your iPod, too. Update: As many of you pointed out, there are multiple places to get your full genome scanned now for prices in the mere thousands of dollars. Pocket change, really.