Microneedles
Latest
Vaccine-delivery patch uses microneedles to do its dirty work, looks good in testing
This dissolving microneedle patch has been in development for well over a year now, but Mark Prausnitz -- a professor in the Georgia Tech School of Chemical and Biomolecular Engineering -- along with a number of other GT and Emory University colleagues, have just now wrapped up a lab trial that brings it that much closer to market. As the story goes, this vaccine-delivery patch, which is based on hundreds of microscopic needles that dissolve into the skin, was recently seen as reliable in a round of mice tests, and the powers that be have also concluded that these patches would cost "cost about the same as conventional needle-and-syringe techniques, and may lower the overall cost of immunization programs by reducing personnel costs and waste disposal requirements." Oh, and did we mention that you could apply 'em on your own with little to no pain? FDA approval, we're waitin' on ya.
Ceramic microneedles to make injections painless
Rest assured, we've "seen" methods of delivering injections sans pain, but we've yet to actually experience this phenomenon ourselves. If Dr. Roger Narayan has anything to do about it, however, we may not feel even a pinch the next time the blood drive comes calling. A team of researchers led by the aforementioned individual has reportedly been able to use "two-photon polymerization of organically modified ceramic (Ormocer) hybrid materials to create microneedles resistant to breakage," and they can also be made in a wider range of sizes than metal counterparts. It's said that these very needles would be "so fine that patients wouldn't feel them piercing their skin," and while that sure sounds delightful, we've no idea how many more visits we'll make before finding one of these in the nurse's hand.[Via medGadget, image courtesy of Rice]
NanoPass needles set to vaccinate sans pain
Given the choice, even we'd take the pills over the vaccination, but a new Israeli startup is hoping to ease the fears so commonly associated with needles. NanoPass Technologies is working to develop its "proprietary intradermal drug delivery technology," which supposedly deliver injections without the painful side effects by actually not reaching the nerve endings of the skin. Based on MicroPyramids, which are manufactured by MEMS (Micro Electro Mechanical Systems), the pure silicone crystals are used in extremely diminutive microneedles for intradermal injections, and the tip of the device measures less than one-micrometer in diameter. The company touts its pain-free technology (sound familiar?) as a breakthrough that is "non-intimitdating," which should reduce the likelihood of fainting both youngsters (okay, and adults) face when dealing with needles, and is even said to be easier to administer. Unfortunately, we've got no good news proclaiming that these will be replacing intramuscular and subcutaneous methods later this week, but the $6.5 million in funding that the company has acquired should go pretty far is helping its cause. [Via MedGadget]
