What should you do when you have a former World Number 1 ranked tennis player on your late night talk show? Challenge her to Wii Tennis, of course!

That's what Conan O'Brien decided to do last night when he had Serena Williams on as a guest. We caution the little ones to avoid direct eye contact with O'Brien's scantily-clad body, as the sheer paleness reflects light and can blind you. Look closely and you'll see that the production team made Miis of the host and guest.

We won't give away the final score, but it was a close game. Video embedded after the break.

[Thanks, Sam]

This article was originally published on Joystiq.